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Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Ayvakit	Avapritinib	2020-01-09	2034	Gastrointestinal stromal tumors
Ayvakyt	Avapritinib	2020-09-24	2034	Gastrointestinal stromal tumors

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

hematologic neoplasms

,

mast-cell leukemia

,

central nervous system neoplasms

,

gastrointestinal stromal tumors

,

systemic mastocytosis

,

healthy volunteers/patients

,

,

chronic renal insufficiency

,

knee osteoarthritis

,

,

,

hepatic insufficiency

,

,

telomeric repeat binding protein 2

,

,

plexiform neurofibroma

,

therapeutic equivalency

,

pharmacokinetics

,

biological availability

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

uveal neoplasms

,

,

,

rhabdomyosarcoma

,

,

,

head and neck neoplasms

,

non-hodgkin lymphoma

,

prostatic neoplasms

,

squamous cell neoplasms

,

pancreatic neoplasms

,

endometrial neoplasms

,

multiple myeloma

,

urinary bladder neoplasms

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

chronic obstructive pulmonary disease

,

esophageal neoplasms

,

serous cystadenocarcinoma

,

colonic neoplasms

,

hematologic neoplasms

,

type 2 diabetes mellitus

,

diabetes mellitus

,

obstructive lung diseases

,

follicular lymphoma

,

uterine neoplasms

,

,

mullerian mixed tumor

,

,

waldenstrom macroglobulinemia

,

,

uterine cervical neoplasms

,

cardiovascular diseases

,

peritoneal neoplasms

,

,

hereditary breast and ovarian cancer syndrome

,

pancreatic ductal carcinoma

,

small cell carcinoma

,

b-cell lymphoma marginal zone

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

respiratory aspiration

,

,

urethral neoplasms

,

ureteral neoplasms

,

pelvic neoplasms

,

castration-resistant prostatic neoplasms

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

epstein-barr virus infections

,

oropharyngeal neoplasms

,

peripheral nervous system diseases

,

malignant mesothelioma

,

,

adrenocortical carcinoma

,

adenocarcinoma of lung

,

salivary gland neoplasms

,

central nervous system neoplasms

,

germ cell and embryonal neoplasms

,

,

pleural effusion

,

malignant pleural effusion

,

thyroid neoplasms

,

,

breast neoplasms

,

,

ovarian neoplasms

,

colorectal neoplasms

,

small cell lung carcinoma

,

large b-cell lymphoma diffuse

,

,

liver neoplasms

,

,

b-cell lymphoma

,

squamous cell carcinoma

,

renal cell carcinoma

,

hepatocellular carcinoma

,

ovarian epithelial carcinoma

,

,

,

stomach neoplasms

,

triple negative breast neoplasms

,

fallopian tube neoplasms

,

biliary tract neoplasms

,

kidney neoplasms

,

neoplasm metastasis

,

squamous cell carcinoma of head and neck

,

brain neoplasms

,

transitional cell carcinoma

,

urologic neoplasms

,

,

communicable diseases

,

hypersensitivity

,

endometrioid carcinoma

,

mucinous cystadenocarcinoma

,

clear cell adenocarcinoma

,

acinar cell carcinoma

,

neoplasms by site

,

gastrointestinal stromal tumors

,

male breast neoplasms

,

non-small-cell lung carcinoma

,

,

,

b-cell chronic lymphocytic leukemia

,

,

lymphoid leukemia

,

mantle-cell lymphoma

,

kidney diseases

,

,

migraine disorders

,

,

,

,

,

,

,

family relations

healthy volunteers/patients

,

colonic neoplasms

,

malignant mesothelioma

,

,

,

bronchiolitis obliterans syndrome

,

lymphoid leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

,

prostatic neoplasms

,

hypereosinophilic syndrome

,

,

systemic scleroderma

,

diffuse scleroderma

,

colorectal neoplasms

,

myeloid leukemia acute

,

,

non-small-cell lung carcinoma

,

ovarian neoplasms

,

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

,

,

ovarian epithelial carcinoma

,

hematologic diseases

,

graft vs host disease

,

chronic disease

,

myeloid leukemia accelerated phase

,

localized scleroderma

,

systemic mastocytosis

,

primary myelofibrosis

,

myelomonocytic leukemia acute

,

,

renal cell carcinoma

,

thyroid neoplasms

,

thyroid diseases

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

,

,

,

,

urogenital neoplasms

,

male genital diseases

,

prostatic diseases

,

abdominal neoplasms

,

male genital neoplasms

,

genital diseases

,

,

aggressive fibromatosis

,

,

neoplasm metastasis

,

non-hodgkin lymphoma

,

,

t-cell lymphoma

,

nephrogenic fibrosing dermopathy

,

b-cell chronic lymphocytic leukemia

,

myelodysplastic syndromes

,

,

hypersensitivity

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

desmoplastic small round cell tumor

,

,

myeloproliferative disorders

,

small cell lung carcinoma

,

dermatofibrosarcoma

,

autonomic nervous system diseases

,

,

rheumatoid arthritis

,

,

,

hematologic neoplasms

,

,

,

pulmonary arterial hypertension

,

familial primary pulmonary hypertension

,

,

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

gastrointestinal stromal tumors

,

philadelphia chromosome

,

myeloid leukemia chronic-phase

,

,

breast neoplasms

,

congenital abnormalities

,

chromosome aberrations

,

chromosome disorders

,

stomach neoplasms

,

polycythemia vera

,

,

multiple myeloma

,

,

plasma cell neoplasms

,

large b-cell lymphoma diffuse

,

castration-resistant prostatic neoplasms

,

colorectal neoplasms

,

esophageal neoplasms

,

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

triple negative breast neoplasms

,

,

,

,

squamous cell carcinoma

,

squamous cell neoplasms

,

penile neoplasms

,

myelodysplastic syndromes

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

,

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

,

communicable diseases

,

prostatic neoplasms

,

soft tissue infections

,

,

myeloid leukemia acute

,

,

ischemic stroke

,

,

myeloid leukemia

,

,

coronary artery disease

,

myocardial ischemia

,

,

pulmonary hypertension

,

,

,

pulmonary arterial hypertension

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

interstitial lung diseases

,

,

,

coronary disease

,

,

atrial fibrillation

,

respiratory syncytial viruses

,

,

,

immunocompromised host

,

breakthrough infections

,

,

rheumatoid arthritis

,

,

renal cell carcinoma

,

kidney neoplasms

,

cardiovascular diseases

,

ulcerative colitis

,

,

,

,

,

,

,

,

nerve degeneration

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

type 2 diabetes mellitus

,

diabetes mellitus

,

respiratory tract infections

,

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